Mesa Boogie Recording Preamp When A Preamp Goes Into The Effects Loop Of An Amp, Does It Bypass/skip The Preamp Of The Amp?

When a preamp goes into the effects loop of an amp, does it bypass/skip the preamp of the amp? - mesa boogie recording preamp

I would like

A Mesa Boogie Rectifier Recording Preamp
In the "back" of the effects loop of my amp wall

if I forget / skip the stage of my amp preamp
only used the amp on stage?